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DeCS
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Descriptor English:
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Complement C2
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Descriptor Spanish:
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complemento C2
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Descriptor Portuguese:
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Complemento C2
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Synonyms English:
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C2 Complement
C2, Complement
Complement 2
Complement Component 2
Complement, C2
Component 2, Complement
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Tree Number:
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D12.776.124.486.274.150
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Definition English:
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A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE). |
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Pharmacological Action:
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Immunologic Factors
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History Note English:
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2006 (1975)
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Allowable Qualifiers English:
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Record Number:
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22134
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Unique Identifier:
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D003175
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Occurrence in VHL:
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Similar:
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DeCS
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